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Adrian Heath: political conservative, artistic radical | Fitzrovia News

Adrian Heath, by Jane Rye. Published by Lund Humphries

Reviewed by Max Neufeld

Oil on canvas.

Ascending Forms, Oil on canvas painted in 1951 by Adrian Heath

The publication of this copiously illustrated monograph on Adrian Heath (1920-1992) is an important event. It recognises and describes Adrian?s major, but still neglected, role in post war British Art.

After finding his feet following three years as a prisoner of war, Adrian conciously became an abstract painter through the study of art theory and intellectual conviction.?As he put it: ?I no longer work from a visual experience but towards one.?

In the early 1950s a group of like minded artists coalesced around Victor Pasmore including Anthony Hill, Kenneth and Mary Martin, and Adrian Heath. As so often in his life Adrian became the active promotor of the group and it was at his flat in 28 Charlotte Street that the first of three exhibitions was held in 1952. They called their work ?Constructed abstract art?.?

Adrian subsequently separated from the group as he was the only one to go on painting while the others created constructions. Adrian developed as an artist over the years and painted many beautiful paintings but there is no doubt that the early- to mid-1950s were his most innovative and important period. During this time his painting had a particular intellectual rigueur and tension.

In his subsequent development particularly the 1970s and 1980s his work became more sensuous with the appearance of abstracted human form in his pictures.

Adrian was in many ways a contradiction: politically conservative and establishment and a member of the Beefsteak Club, but artistically a radical. He believed passionately in the social value of art and in his abstract painting pursued an unpopular aesthetic. He never sought to be fashionable. With his wide knowledge of art theory and related philosophy he was an intellectual but in a country where intellectuals are suspect he carried his knowledge lightly.?He had an encyclopedic knowledge of 19th Century French painting.

In recent years Adrian?s work, particularly that of the 1950s, has become more sought after and it is to be hoped that this in depth?study of his work will further encourage recognition of his importance in a key period of British art and that he will at last be given the long overdue major retrospective at the Tate.

Available from?Ashgate Publishing.

This article was first published in Fitzrovia News no. 127, December 2012.

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Source: http://news.fitzrovia.org.uk/2013/03/31/adrian-heath-political-conservative-artistic-radical/

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95% West of Memphis

All Critics (106) | Top Critics (24) | Fresh (101) | Rotten (5)

A real-life horror story, made no less shocking by the familiarity of its early scenes.

While the "Paradise Lost" films captured events as they unfolded in the heat of battle, "West of Memphis" has the luxury of at least partial closure.

A true-crime story that begins with a notorious murder case and grows into a chilling indictment of the American justice system.

And justice for all? Hardly.

It tells the story of a terrible crime compounded by a grave injustice that's been remedied, but only in part, so it's impossible to have a single or simple response to the movie.

What sets this film apart from previous efforts to document the story is that Jackson and Walsh financed a private investigative team with legal and forensic experts who re-examined old evidence, conducted new interviews and found new witnesses.

The film is so utterly transfixing you won't believe almost two-and-a-half hours have passed when the final credits roll.

We feel like we're watching an overlong true-crime television episode and not a movie.

I would have preferred Jackson's clinically-presented project display a bit more reverence for the three young lives that were brutally taken some twenty years ago.

Moving and gruesome, West of Memphis is an eloquent disquisition on the banality of evil.

"West of Memphis" re-examines evidence and retells the story in a methodical and procedural fashion in which even the false steps lead somewhere.

More a recap and appendix to the Paradise Lost trilogy... one can't help but feel that the celebrities involved needed this document of their efforts to appease their vanity.

The case is more intriguing than the film about it.

Isn't unnecessary, but it's often superfluous.

The film suggests these powerless, poorly educated young men were scapegoated because they would be missed by nobody of importance -- the justice system equivalent of the cannon fodder recruited from the same socioeconomic straits.

It's nice to have all the twists and turns of the iconic case contained tidily in one well-crafted film, although there are no real revelations here.

"West of Memphis" becomes a greatest-hits concert of prosecutorial misconduct, and you'll agree when the film asserts that prosecutors knew they had the wrong guys.

Incredibly, after three documentaries on the subject, there are still things to reveal about the West Memphis Three.

"West of Memphis" does nothing to displace its predecessor films as masterpieces of investigative filmmaking, but complements them as a riveting capstone to an epic and tragic tale.

West of Memphis is the real vindication - even if it is incomplete.

In the end it won't matter if this is the fourth movie about the same subject; you can never learn its lessons often enough.

West of Memphis caps off the Paradise Lost/West Memphis Three saga with a line up full of perpetrators including the media, the West Memphis PD, the legal establishment and suspect gift wrapped with a smoking gun.

Injustice in West Memphis, Arkansas

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Source: http://www.rottentomatoes.com/m/west_of_memphis/

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No end to Italy deadlock as president meets parties

By James Mackenzie

ROME (Reuters) - Italy's political parties remained far apart on Friday as President Giorgio Napolitano searched for a way out of the month-long stalemate since deadlocked elections left no group able to form a government alone.

Napolitano met political leaders on Friday after center-left chief Pier Luigi Bersani, who won the largest share of the vote but fell short of a majority in parliament, failed to reach a deal with other parties that would allow him to govern.

Former Prime Minister Silvio Berlusconi insisted that the only solution was for Bersani to accept a coalition deal that would give the media tycoon a share in power but he was immediately rebuffed by a senior Democratic Party official.

The 76-year-old billionaire said there was "no other solution" than a coalition and he ruled out backing a technocrat government like the one led by outgoing Prime Minister Mario Monti, whom he blames for pushing Italy into recession.

"Our position has not changed. We expressed it with absolute clarity to the president," center-right leader Berlusconi told reporters after the meeting with Napolitano.

Luigi Zanda, Senate leader for Bersani's Democratic Party(PD), said it was "very difficult" to imagine a coalition with Berlusconi's People of Freedom (PDL) party.

"There are too many important issues in PDL policies that are light years from those of the Democratic Party," he told SkyTG television.

After five days of talks that ended on Thursday, Bersani failed to get a deal with either Berlusconi or Beppe Grillo's populist 5-Star Movement, which holds the balance of power.

Five Star repeated on Friday that it would not back a government led by any of the big parties it blames for Italy's social and economic crisis. It also rejected any "pseudo-technocrat" administration.

"Give them a vote of confidence? Those are swear words in the mouths of people like them," Grillo said in a live video broadcast on his popular blog. "They should all just go home."

A deal between center-right and center-left has been blocked by Bersani, who says Berlusconi is untrustworthy and also rejects the latter's demand to nominate a successor to Napolitano, whose mandate expires in May.

Berlusconi said there had been no deal on the presidency but it was "in the logic of things that if you form a coalition government you discuss the best president of the Republic".

PRESIDENT TAKES THE INITIATIVE

After Bersani's failure, the 87-year-old Napolitano is holding a quick round of meetings with the main parties to assess what options remain to prevent another election.

The refusal by Berlusconi and his allies in the Northern League as well as Grillo to back a technocrat government appears to narrow his options greatly and made it much less likely that an independent figure will be able to lead a non-political administration - which many see as the only way out of deadlock.

"We were against the Monti government and if there is to be another government of that type it's a thousand times better to have new elections," League leader Roberto Maroni said.

Among the names which had been considered possible candidates as a technocrat leader are Fabrizio Saccomanni, director general of the Bank of Italy or the head of the constitutional court Franco Gallo.

The political gridlock has fed growing worries about Italy's ability to confront a prolonged economic crisis that has left it in deep recession for more than a year, with a 2-trillion-euro ($2.6-trillion) public debt and record unemployment, especially among the young.

Rumors have been circulating for days that ratings agency Moody's is preparing to cut its rating on Italy's sovereign debt, which is already only two notches above "junk" grade, partly due to the uncertain political outlook.

Napolitano has made clear that he does not want Italy to go back to new elections immediately, not least because the widely criticized election law is likely to just repeat the deadlock.

But many are already preparing to vote again, with Berlusconi's center-right confident that the momentum created by his surge towards the end of the last campaign will continue.

A poll by the SWG company on Friday showed the center-right had pushed Bersani's bloc into second place since the vote.

($1 = 0.7788 euros)

(Additional reporting by Naomi O'Leary; Editing by Barry Moody and Michael Roddy)

Source: http://news.yahoo.com/italys-president-seeks-way-political-deadlock-091517168.html

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Syrian rebels enter strategic Aleppo neighborhood

In this Thursday March 28, 2013 image taken from video obtained from the Ugarit News, which has been authenticated based on its contents and other AP reporting, shows a building at the Syrian government checkpoint on fire, in Dael less than 15 kilometers (10 miles) from the Jordanian border in Daraa province, Syria. Thursday, March 28, 2013. Syrian rebels on Friday captured a strategic town near the border with Jordan after a day of fierce clashes that killed dozens of people, activists said, as opposition fighters expand their presence in the south, considered a gateway to Damascus. (AP Photo/Ugarit News via AP video)

In this Thursday March 28, 2013 image taken from video obtained from the Ugarit News, which has been authenticated based on its contents and other AP reporting, shows a building at the Syrian government checkpoint on fire, in Dael less than 15 kilometers (10 miles) from the Jordanian border in Daraa province, Syria. Thursday, March 28, 2013. Syrian rebels on Friday captured a strategic town near the border with Jordan after a day of fierce clashes that killed dozens of people, activists said, as opposition fighters expand their presence in the south, considered a gateway to Damascus. (AP Photo/Ugarit News via AP video)

In this Thursday March 28, 2013 image taken from video obtained from the Shaam News Network, which has been authenticated based on its contents and other AP reporting, shows Syrian Free Army fighters in Dael less than 15 kilometers (10 miles) from the Jordanian border in Daraa province, Syria. Syrian rebels on Friday captured a strategic town near the border with Jordan after a day of fierce clashes that killed at least 38 people, activists said, as opposition fighters expand their presence in the south, considered a gateway to Damascus. (AP Photo/Shaam News Network via AP video)

In this Thursday March 28, 2013 image taken from video obtained from the Shaam News Network, which has been authenticated based on its contents and other AP reporting, shows heavy clashes between Syrian Free Army fighters and the regime?s army in Dael less than 15 kilometers (10 miles) from the Jordanian border in Daraa province, Syria. Syrian rebels on Friday captured a strategic town near the border with Jordan after a day of fierce clashes that killed at least 38 people, activists said, as opposition fighters expand their presence in the south, considered a gateway to Damascus. (AP Photo/Shaam News Network via AP video)

(AP) ? Syrian rebels pushed into a strategic neighborhood in the northern city of Aleppo after days of heavy clashes, seizing control of at least part of the hilltop district and killing a pro-government cleric captured in the fighting, activists and state media said Saturday.

There were conflicting reports about the scale of the advance into the Sheikh Maqsoud neighborhood by rebel forces battling to topple Syrian President Bashar Assad. But the gains marked the biggest shift in the front lines in the embattled city in months.

Aleppo, Syria's largest city and a former commercial hub, has been a key battleground in the country's civil war since rebels launched an offensive there in July, seizing several districts before the fighting largely settled into a bloody stalemate.

The Aleppo Media Center opposition group and Aleppo-based activist Mohammed Saeed said rebels seized full control of Sheikh Maqsoud late Friday.

The Britain-based Syrian Observatory for Human Rights, however, said rebels took only the eastern part of the neighborhood, and reported heavy fighting there Saturday.

Syria's state news agency SANA said government troops "eliminated scores of terrorists" in other parts of Aleppo mainly in the neighborhoods of Sheikh Said, Masaken Hanano and Bustan al-Bacha. SANA did not mention the fighting in Sheikh Maqsoud.

Sheikh Maqsoud, which is predominantly inhabited by minority Kurds, is located on a hill on the northern edge of the city. The neighborhood used to be known as "Our Lady's Mountain" and is considered one of the most strategic locations in the city because it overlooks much of Aleppo.

Activists predicted that regime forces would launch counterattacks to try to retake the area because if rebels keep holding Sheikh Maqsoud it will be easy for them to target regime-held areas with mortar shells.

The media center and the Observatory both reported that residents were fleeing the neighborhood to safer areas. The media center said regime tanks around the neighborhood were shelling the area.

An amateur video showed about two dozen gunmen standing in front of a building owned by the Syrian government. In the video, one of the gunmen claims that rebels and their "Kurdish brothers liberated Sheikh Maqsoud of Assad's criminal gangs and shabiha" or pro-government militiamen.

The video appeared genuine and corresponded to other reporting that The Associated Press did on events depicted in the footage.

Saeed, the Aleppo-based activist, said several rebel groups, including Kurdish gunmen, took control of the neighborhood after launching an attack, titled "Kurdish Fraternity," on Thursday. He said that on Saturday fighting intensified on the eastern edge of the area around an army post known as Awamid.

The Observatory said rebels captured a pro-government Sunni Muslim cleric in the fighting, killed him and then paraded his body through the neighborhood.

State-run Al-Ikhbariya TV identified the cleric as Hassan Seifeddine. It said he was beheaded and his head was placed on the minaret of Al-Hassan Mosque where he used to lead the prayers.

The SANA state news said Seifeddine's body was "mutilated" after the "assassination."

The reports of the mutilation of the cleric's body could not be independently confirmed.

The killing of Seifeddine comes nearly 10 days after a suicide bomber blew himself up inside a mosque in the heart of the Syrian capital, Damascus, killing top Sunni preacher Sheik Mohammad Said Ramadan al-Buti as he was giving a sermon. The March 21 blast killed 48 others and wounded dozens.

Al-Buti, like Seifeddine, was a strong supporter of the Assad regime, which is dominated by members of the president's minority Alawite sect, an off-shoot of Shiite Islam. The opposition is made up of mostly Sunnis, who are the majority among Syrians.

Extremists have been playing a larger role among the rebel groups. They include the Islamic Jabhat al-Nusra, a powerful offshoot of al-Qaida in Iraq, which has claimed responsibility for most of the deadliest suicide bombings against regime and military facilities and, as a result, has gained popularity among some rebels.

A photograph recently posted online by activists showed Seifeddine, who was in his late 50s and had a white beard. A banner posted over the picture said: "A wanted agent." Another referred to him as wanted by the rebels and read: "An agent of Syria's ruling gang and wanted by the Free Syrian Army."

Aleppo-based Sunni cleric Abdul-Qadir Shehabi told state-run TV that Seifeddine's son was kidnapped months ago. Shehabi also lashed out at the rebels, saying they "mutilated" Seifeddine's body.

"Is this the freedom that they talk about? This is the freedom of Satan," Shehabi said, referring to rebels who say they are fighting Assad's regime because it is authoritarian.

Rami Abdul-Rahman, who heads the Observatory, said Seifeddine's name had been put on an opposition "death list."

"He was the imam of a mosque. He was not armed when he was killed," Abdul-Rahman said. "We cannot close our eyes when the opposition violates human rights."

Abdul-Rahman said that although Sheikh Maqsoud is predominantly Kurdish, the eastern areas where much of the fighting occurred are inhabited by pro-regime Sunni Muslims known as the "Mardilis." Many of them came to Aleppo decades ago from Turkey's southeastern province of Mardin. He said Seifeddine was one of them.

Elsewhere in Syria, activists reported violence in areas of the southern province of Daraa, the suburbs of Damascus and the northern regions of Idlib and Raqqa. The Observatory said the heaviest clashes were in Raqqa and Sheikh Maqsoud.

Abdul-Rahman said the fighting in Sheikh Maqsoud killed 14 pro-government gunmen, seven rebels, 10 civilians and Seifeddine.

The Observatory said rebels were fighting a fierce battle around an army post known as the Camp in the oil-rich eastern province of Deir el-Zour, which borders Iraq.

In Damascus, residents said power was cut on Saturday in some neighborhoods. Al-Ikhbariya TV quoted Minister of Electricity Imad Khamis as saying the network suffered a technical problem that would be fixed in 24 hours. Damascus has witnessed repeated cuts in recent months.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-03-30-ML-Syria/id-94c190c83f4c4faa8dd90da44c7dd92a

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Sniper: Ghost Warrior 2. ??? ? ?????????? ??????? - ?????????? ...

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"?????????: PC, PS3, Xbox 360, PS Vita, Wii U"
??????? ???????? ?? ????? ????????? ?? ????????? ????, ???? ?????? ????????? ? ???? ?????????. ???????.

Source: http://forums.ferra.ru/index.php?showtopic=55200

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ImSyndicate -BF3 Prof - ADK= Gaming Community

Hello ImSyndicate,

?

My real name is Joachim, and im from Denmark, in Scandinavian. Im 16 years old and im goin in 9th grade. I love to play computer games, and soccer. Im always trying to improve my gaming skills, so i can be the ?best. Training is the way

?

/ImSyndicate


Source: http://www.adkgamers.com/topic/25235-imsyndicate-bf3-prof/

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Snag a copy of ?Windows 8 Security (Free eBook offer expires on 4/4)?

Windows 8 Security [affiliate link] is an eBook that will help you make the most of the enhanced security features that have been added to the new Windows 8 operating system. Some topics covered are?Dynamic Access Control, BranchCache, DirectAccess, BitLocker, Virtualization, Social Media, SmartScreen and WindowsToGo. There are a few hoops to jump through to [...]

Source: http://the-gadgeteer.com/2013/03/29/snag-a-copy-of-windows-8-security-free-ebook-offer-expires-on-44/

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Andrei Arlovski?s camp says timing error in New Jersey caused him to take ?huge blow? late

Just days after Nick Diaz's camp criticized the athletic commission in Quebec for their handling of his UFC 158 weigh-in with UFC welterweight champ Georges St-Pierre, another athletic commission is under fire. Jackson's MMA, the gym who backs Andrei Arlovski, said a timing error by the New Jersey State Athletic Control Board resulted in Arlovski's broken jaw.

Arlovski lost to Anthony Johnson in a World Series of Fighting bout on Saturday. Jackson's MMA posted on their Facebook about the timekeeping problem:

The NJ athletic commission was worried about the World Series of Fighting getting a new canvas and new corner pads for the cage they almost canceled the fight Saturday night. Unfortunately they forgot to get a time keeper that was trained properly. 1st round 5min 8 sec in the Andrei fight. A devastating blow was landed after the 5min mark. It's amazing how so much time is spent with over regulating but the simple things can cost dearly.

WSOF had to bring in a new canvas and pads when the ones they originally had were unsuitable. But the timing error is much worse. Check out this video via MMA Fighting, and listen to the wood clacking at the 10-second mark. The clock disappears from the screen at seven seconds. Even a generous countdown shows the fight went past the five-minute mark.

The worst part is that the damage Johnson caused came after the time should have expired. His jaw was broken, and it needed surgery for repair. It also raises questions on if the fight result would have been different if Arlovski wouldn't have been hurt late in the first round.

Memorable Moments from Yahoo! Sports:

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Source: http://sports.yahoo.com/blogs/mma-cagewriter/andrei-arlovski-camp-says-timing-error-jersey-caused-144726034--mma.html

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Spice Giveaway from Cooking Planit ? Creative Culinary :: Food ...

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I?m so excited to announce that I?m giving away a Spice Set from CookingPlanIt! It?s an awesome set of spices that includes 26 of the most commonly used spices in the kitchen:

Ground Cumin
Basil
Saigon Cinnamon
Bay Leaves
Smoked Paprika
Thyme
Garlic Powder
Mediterranean
Oregano
Onion Powder
Rosemary
Nutmeg Powder
Red Pepper Flakes
Coriander Powder
Cayenne Pepper
Ground Cloves
Chinese Five Spice
Turmeric
Curry Powder
Yellow Mustard
Pennsylvania Pepper
Cardamon Powder
Cajun Seasoning
Allspice Powder
Hill Country Chili Powder
Ginger Root Powder
Manzanillo Mexico Seasoning

The?Cooking Planit Spice Giveaway is a fabulous promotion sponsored by the folks at Cooking Planit. They?re giving 50 spice sets to foodie, mommy and tech bloggers to give away to their readers in any way that they would like and two sets were given away each day for 25 days with the first contests starting on March 4th. If you missed winning before; here is another chance!

spices-4

Cooking Planit is a recipe site that is organized by meals and not just as individual recipes; the guesswork it taken out of what to serve together. I also love that they test every recipe on the site; nothing I hate more than trying something that is a big huge #FAIL! Add to that cooking tips, organizational ideas and more and you?ve got a great site for cooks with any level of experience.

Winning is easy?just leave a comment letting me know what your favorite spice is and you?ll be entered. My contest runs through April 5th, 2013 at midnight EST and a winner will be picked April 6th. Good luck!

Check out the other foodies below who participated and find the others who are still running an active contest?more chances for you to win!

spices-2

This giveaway is sponsored by Cooking Planit; all opinions are my own.?Images courtesy Cooking Planit.

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Source: http://www.creative-culinary.com/spice-set-giveaway-from-cookingplanit/

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Astronauts Launch on First 'Express' Flight to Space Station

A Soyuz rocket carrying an American astronaut and two Russian cosmonauts roared into space today on the first-ever "express" flight to the International Space Station.

The rocket launched NASA astronaut?Chris Cassidy?and Russian cosmonauts Alexander Misurkin and Pavel Vinogradov into orbit at 4:43 p.m. EDT?(2043 GMT) from the Baikonur Cosmodrome in Kazakhstan, where the local time was early Friday. The crew's Soyuz TMA-08M spacecraft is expected to make history when it arrives at the space station later tonight.

The Soyuz crew plans to dock at the space station's Poisk module tonight at 10:32 pm EDT (0232 GMT Friday). You can watch the space docking live on SPACE.com here.

Until today, Soyuz and NASA shuttle trips to the space station typically took at least two days, but Cassidy, Misurkin and Vinogradov are due to?arrive in just six hours, after making only four orbits of Earth. Some NASA officials have dubbed the flight profile, the "express" flight to the International Space Station.

"I think this is a very good thing that we are decreasing the time that it takes for crews to reach the International Space Station," Vinogradov said in a pre-launch interview. "I'm confident that both in Russia and in the United States we have excellent teams that are supporting us." [Launch Photos: Soyuz Rocket's 'Express' Flight to Station]

The quick trip to the space station has been made before by unmanned cargo spacecraft, but never by a crew. Mission managers say its benefits include less time spent in a cramped space by the crew, and a savings on expenses related to the personnel needed in Mission Control when Soyuz is flying.

Once there, they will join the existing station residents ? commander Chris Hadfield of Canada, Russian cosmonaut Roman Romanenko, and NASA astronaut Tom Marshburn ? on the station's?Expedition 35 mission. The newcomers are due to stay in space for about six months.

"It's shaping up to be a very dynamic and a very busy expedition," Cassidy said during a pre-launch interview. "We welcome that ? that makes us feel very rewarded and high job satisfaction. When you can deliver for people that have worked hard to produce all of those activities on the ground, that's very satisfying," he said of the ability to fulfill the goals of the Mission Control team.

Cassidy and Vinogradov are both spaceflight veterans: The former flew on the STS-127 space shuttle mission in 2009, while Vinogradov visited the Russian Mir space station in 1997 and the?International Space Station?in 2006. Misurkin, a spaceflight rookie, is making his first journey to orbit.

"I'm just really excited and looking forward to this flight," he said in a preflight interview. "I think it would be a great experience for me and the biggest thing in my whole life."

In between their busy schedules of science experiments, space station maintenance and spacewalks for station upkeep, the spaceflyers hope to find some down time to appreciate their environment.

Vinogradov is an astronomy buff and said he looks forward to the view of the heavens from space.

"I think I'm very fortunate that I have this unique opportunity to perform space observations from space," Vinogradov told SPACE.com in a preflight interview. "Every time I get a spare minute I plan to practice astronomy. I cant promise or guarantee that this will happen every day, because our flight program is very busy, but I am planning to use every opportunity to do that."

Vinogradov is scheduled to take over command of the space station from Hadfield in May when Hadfield, Romanenko and Marshburn return to Earth. Vinogradov, Cassidy and Misurkin are due to return home in September.

Follow Clara Moskowitz?@ClaraMoskowitz?and?Google+. Follow us?@Spacedotcom,?Facebook?and?Google+. Original article on?SPACE.com.

Copyright 2013 SPACE.com, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/astronauts-launch-first-express-flight-space-station-210306275.html

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Play of the Day: The Many Views of Marriage

By Martyn Herman LONDON, March 28 (Reuters) - Whether by design, necessity, self-interest or because of all three, nurturing youngsters has become fashionable for England's elite with no expense spared in the hunt for the new Wayne Rooney or Steven Gerrard. The length and breadth of the country, scouts from top clubs are hoovering up promising footballers barely old enough to tie their bootlaces in a bid to unearth the 30 million pounds ($45.40 million) treasures of the future. ...

Source: http://news.yahoo.com/play-day-many-views-marriage-112149631--politics.html

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US sends nuclear-capable B-2 bombers to SKorea

SEOUL, South Korea (AP) ? The U.S military says two nuclear-capable B-2 bombers have completed a training mission in South Korea amid threats from North Korea that include nuclear strikes on Washington and Seoul.

The statement Thursday by U.S. Forces Korea is an unusual confirmation. It follows an earlier U.S. announcement that nuclear-capable B-52 bombers participated in ongoing U.S.-South Korean military drills.

The U.S. says the B-2 stealth bombers flew from a U.S. air base and dropped munitions on a South Korean island range before returning home.

The announcement will likely draw a strong response from Pyongyang. North Korea sees the military drills as part of a U.S. plot to invade and becomes particularly upset about U.S. nuclear activities in the region.

Washington and Seoul say they the annual drills are routine and defensive.

Source: http://news.yahoo.com/us-sends-nuclear-capable-b-2-bombers-skorea-112309292.html

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Knox case puts Italian justice under scrutiny

ROME (AP) ? When crooked American financier Bernie Madoff was sentenced in New York, the leading Italian newspaper Corriere della Sera published a front-page cartoon mocking Italy's trial system.

On one side was a U.S. courtroom, where a judge was handing down a 150-year sentence after a six-month trial. On the other, an Italian courtroom with a judge handing down a six-month sentence after a 150-year trial.

That's how the country's No. 1 newspaper summed up Italy's slow-moving, and at times inconclusive, justice system.

The decision by Italy's highest criminal appeals court to overturn the acquittals of American student Amanda Knox and her former Italian boyfriend, and order a new trial in the 2007 slaying of her British roommate, is once again raising concerns both at home and abroad about how justice works in Italy.

It's a system where people cleared of serious crimes can have the threat of prison hanging over them for years, while powerful politicians such as former premier Silvio Berlusconi can avoid jail sentences almost indefinitely by filing appeal after appeal until the statute of limitations runs out.

"Lots of confusion and contradictions," said restaurant chef Angelo Boccanero, giving his impression of the Knox case as he sipped his morning espresso.

And it's not just the criminal courts that raise eyebrows.

The back log on civil cases is so severe that it hampers desperately sought foreign investment to Italy. Divorces can take years to process, meaning that couples who've had enough remain legally tied. And forget about getting quick compensation in a fraudulent property deal ? it can take ages (if ever) before you'll see any money.

Successive governments have pledged to streamline proceedings but have so far failed to do so. That's largely because powerful people in politics, business and the judiciary have repeatedly fended off reform to protect their interests and the people close to them.

One criticism of the system is Italy's high number of lawyers. Milan, for example, has more attorneys than all of France. In civil cases, it takes an average of seven years to reach a verdict.

Defenders say that Italy's legal system is one of the world's most "garantista" ? or protective of civil liberties. Defendants are guaranteed three levels of trial before a conviction is considered definitive and both sides are granted the right to appeal ? although prosecutors often don't appeal minor acquittals. It's a system that sprang up in the postwar era to prevent the travesties of summary justice seen under fascist dictator Benito Mussolini, but in reality it means that justice can be delayed until it's denied as cases move at a snail's pace through the bloated legal machine.

Italy is also one of the leading voices in the world in campaigns to abolish capital punishment. In 1996, Italy refused to extradite one of its citizens wanted for murder in Florida, saying it did not receive sufficient guarantees he would not risk execution if convicted. He was tried in Italy, convicted and sentenced to 23 years in prison.

For Knox, the system allowed new evidence in the appeals trial that led to her 2011 acquittal. But it also is exposing her to a third trial ? which in all likelihood will be followed by another round at the supreme court. Knox is not expected to attend her retrial. If she is convicted ? and the conviction is upheld by highest criminal court ? Italy could seek her extradition. The United States law allows extradition of its citizens.

Another key aspect of the Knox case: The Italian system does not include U.S. Fifth Amendment protection against a defendant being put in double jeopardy by government prosecution.

"Our judicial system, like all judicial systems, is fallible," said Stelio Mangiameli, a constitutional law expert at Rome's LUISS University, but added: "It's not worse or better than the United States."

He said that, in addition to guarantees for the defense, Italy takes pains to protect the rights of the victim.

"You need to consider when there is a crime, there is also a victim," said Mangiameli. "In the Amanda Knox case, there is a dead girl and someone needs to respond for this death, no matter if American or French or any other nationality."

But the process, which in some cases runs over decades, can leave people like Knox in judicial limbo.

In September, an Italian civil court ordered the government to pay 100 million euros in civil damages to relatives of 81 people killed in a 1980 air disaster whose cause has been attributed alternately to a bomb on board and to being caught in an aerial dogfight. The court held that the transport and defense ministries had concealed the truth, even though a criminal court acquitted two generals for lack of evidence five years earlier.

It would seem natural that after three decades, the September decision meant the case was closed. Instead, appeals are pending.

For two decades, Berlusconi has been moving from trial to trial on charges that include corruption, tax fraud and sex-for-hire. He has described himself as an innocent victim of prosecutors he routinely slams as communists.

The ex-premier has so far never had a conviction upheld by the highest court and never served any time in jail. His lawyers employ vigorous defense techniques that have included laws ? one struck down as unconstitutional ? blocking top government officials from prosecution. As premier, Berlusconi himself has enacted legislation that is widely seen as tailor-made to shield him from legal difficulties.

Sometimes, however, justice is served.

Parmalat founder Calisto Tanzi is serving an eight-year sentence on market rigging related to the stunning 2003 collapse of his dairy empire despite his advanced age. Tanzi, now 74, has been jailed since 2011 for his role in the scandal that defrauded thousands of small-time investors, despite arguments by his lawyer that his health is failing and that he should be granted house arrest under a law allowing it for convicts over age 70.

Tanzi faces even more jail time ? nearly another 18 years ? on a conviction of fraudulent bankruptcy and criminal association in the 4 billion euro bankruptcy. There is one more appeal on that sentence.

Whether the 25-year-old Knox, who spent four years in prison during the investigation, trial and first appeal, ever returns to Italy to serve more prison time depends on a string of unknowns.

Should she be convicted by an appeals court in Florence court, she could appeal that verdict to the Cassation Court, since Italy's judicial system allows for two levels of appeals ? by prosecutors and the defense. Should that appeal fail, Italy could seek her extradition from the United States.

In defending Italy, some experts say the system cuts both ways.

"If she had been wrongly convicted," said criminal lawyer Manrico Colazza, "she would have been happy there was a court to reverse it."

___

AP correspondent Colleen Barry contributed from Milan.

Source: http://news.yahoo.com/knox-case-puts-italian-justice-under-scrutiny-114859845.html

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How to Believe in Yourself in the Face of Overwhelming Self-Doubt ...

Self-Doubt

?When you doubt your power, you give power to your doubt.? ~Honore de Balzac

You know what that voice in your head says?

You can?t do it. You?ll never be good enough. You?re going to fail.

This voice taunts you whenever you set a goal. It criticizes you when life gets difficult. It beats you down when you struggle to stand up against its running commentary.

You know you shouldn?t let self-doubt bother you, but it?s a sneaky critter. Sometimes, you just can?t contain it and it slips past your barriers.

And self-doubt is greedy. When it?s loose, it devours your confidence, strips logic and reason from your mind, and steals happiness from your heart. In return, it leaves you with only fear and insecurity.

You try to remove self-doubt by forcing yourself to ?think positive,? which usually doesn?t work as well as you think it should.

The more you fight your self-doubt, the more it fights back.?However, with self-knowledge and understanding, you can use self-doubt for your?benefit.

A Story about Crushing Dreams and ?Being Realistic?

When I was a child, I was in love with drawing.?For me, drawing was as exciting as going to the playground.

At some point in my childhood, I decided I?d become an artist of some kind. But the critics in my life were quick to cut me down. I?ll bet you?ve heard the same kind of clich?s:

?Art is great but not a ?realistic? future goal. While it?s a nice?hobby?to have, you can?t really make a living out of it.?You?ll just be another starving artist.?

As children, we internalize these negative messages and parrot them back. If the adults say so, it must be true, right? By adulthood, every time we have a small hope, we?re the first to snuff it out:

?Drawing is nice but not necessary. I?ll never be as good as the real professionals anyway.?I don?t even have a degree from an accredited art school.?

For years, I stopped myself before I even tried. I did it because I was afraid.

I was afraid of what people would say. I was afraid everyone would hate my?art. I was afraid of failing as an artist.

When fear grabs you, your beloved goal forever feels out of reach. But it doesn?t just stop there, does it?

If left unchecked, the infectious bite of fear and self-doubt can spread. You unconsciously start questioning your knowledge and abilities in everything you do.?And if you?re like me, you desperately want to find a cure.

One fateful day, I realized that trying to beat out my self-doubt wouldn?t rebuild my confidence.

If I wanted to believe in myself, I needed to face my self-doubt and be willing to?take care?of it.

Before, I imagined self-doubt as a life-sucking monster. Now, I realize it?s actually a fearful, angry, and lost creature secretly crying for help.

Like fear, joy, and sadness, doubt is part of human nature, and it needs understanding. If you want to improve yourself, you need to tame your self-doubt, not fight with it.

That means paying attention to how you react to things, understanding the root of your insecurities, and taking steps to address your fears.

Now, I no longer tell myself, ?I?ll never be a good enough artist.? Instead, I?ask myself,??What can I do to become better?? And I take baby steps.

I went from drawing every few weeks, to every week, and now every two to three days. Re-framing self-doubt has also helped me cope with other challenges, like successfully starting a small business.

Self-doubt doesn?t have to be as monstrous as we make it out to be. It?s all about perspective. The following tips will help you manage your self-doubt.

Identify and ease your doubts.

Learning how to recognize when your self-talk takes a turn for the worse is crucial. When you hear yourself saying, ?I can?t,? or, ?I don?t know,? or, ?What if,? a red flag should go up.

Instead of telling yourself, ?I can?t do X,? say, ?I can?t do X,?yet.?But I?m working on it.?

Or if you start wondering, ?What if I fail?? you can respond by saying, ?Then I?ll try again.?

Doing this transforms a negative situation into an opportunity for growth. In the end, it?s about giving yourself a chance.

Stop listening to toxic people.

Toxic people are convinced that everything is impossible, and they are quick to shoot down ideas.?They?ll poison your mind into a state of hopelessness.

Don?t let them steal your energy just because they?ve lost theirs.

Instead, surround yourself with supportive and passionate people who can both inspire you and bring out the?best?in you. You can find them among friends, family, books, or blogs like Tiny Buddha.

They will lift you up when you feel down and help you see the bright side of your darkest fears and doubts.

Recall your successes.

This one is tough. When you?re down, you?ll more easily remember the bad instead of the good.?And oftentimes, the ?rah-rah? pep talk just doesn?t cut it.

So, I suggest writing a list. Grab a piece of paper or small notebook, or open a blank document. Now write down your successes, big or small.

If you?re a bit bashful about your achievements, ask someone you trust to tell you the great things they think you?ve done. It?s refreshing and a great confidence boost.

And finally, keep your list with you at all times. It will help you find your way back to yourself whenever you get lost.

Trust and love yourself.

You probably spend more time being your own worst enemy instead of being your own best friend.

But you deserve to treat yourself better. After all, you have the rest of your life to spend with yourself.

Think of it this way: Would you mentally abuse or condemn your loved ones? Would you let them suffer in their time of need? If not, then why would you do it to yourself?

So, be kind to yourself.?You are more capable and worthy than you give yourself credit for.

Give yourself permission to try?and try again.

Self-doubt never disappears. Over time, you just get better at dealing with it.

It will greet you every time you fall out of your comfort zone and whenever you strive to do something great.

But know that it?s not something you have to fear or resent. Your doubts are only thoughts, not your future.

Sure, something may go wrong. But if you never try, you?re losing an opportunity to improve your life.

Are you willing to risk that instead?

SOURCE: http://tinybuddha.com/blog/how-to-believe-in-yourself-in-the-face-of-overwhelming-self-doubt/

Source: http://brookeaddison.com/how-to-believe-in-yourself-in-the-face-of-overwhelming-self-doubt/

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Questionable Entries Prompt Google To Retract Some Glass Explorer Invitations

Greg_Glass_framesGoogle made plenty of nerds happy earlier today when it began reaching out to the 8,000 people that would have the privilege of spending $1,500 on the company's head-mounted Glass display, but that thrill wound up being short-lived for some. About seven hours after announcing that the outreach to would-be Glass Explorers began, the Glass team once again took to the project's Google Plus page to admit they needed to rescind some of those invitations.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/UAqMP8hih0Y/

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4th GCC Government and Business 2020 Human Resources ...

The event was graced by the presence of various keynote speakers and delegates who have made a mark transforming the HR map of the region.

Day 2 was initiated with the presentation of Ms. Clare Woodcraft, Chief Executive Officer, Emirates Foundation, wherein she focused on the challenges and opportunities encountered by GCC nationals in the private sector.

Dr. Othaman Al Khoori, VP HR and Administrator, Abu Dhabi Airport Company, focused on the various strategies that can help in achieving success in the Emiratization policies that have been implemented in the organizations.

Mr. Abdulhussain Tejani, on the second day focused on the significance of integration in HR workplace and addressed the issue of creating a new direction towards building new culture in an organization.

Dr. Ahmed Tahlak elaborated his views on the strategies to achieve and compete for international positions in a globally competitive economy.

He emphasized on the need to develop the eminence of young leadership training programs and the reasons that are hindering the nationals from breaking the monopoly of some countries in international position leadership.

The fourth edition of this conference plays an extraordinary role in supporting, educating, orienting, and promoting competitive HR strategies for bringing a transformational change in the development of regional and national leadership in a globally competitive economy.

Datamatix has been a leading knowledge and service provider in the GCC for 24 years, welcoming businessmen, intellectuals, leaders and professionals and providing valuable business and leadership advice for change by promoting development and economic empowerment.

Source: http://www.ameinfo.com/4th-gcc-government-business-2020-human-335175

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বৃহস্পতিবার, ২৮ মার্চ, ২০১৩

Weekly Radar-?Slow panic? feared on Cyprus as central banks meet ...

US MARCH JOBS REPORT/THREE OF G4 CENTRAL BANKS THURS/NEW QUARTER BEGINS/FINAL MARCH PMIS/KENYA SUPREME COURT RULING/SPAIN-FRANCE BOND AUCTIONS

Given the sound and fury of the past fortnight, it?s hard not to conclude that the messiness of the eventual Cyprus bailout is another inflection point in the whole euro crisis. For most observers, including Mr Dijsselbloem it seems, it ups the ante again on several fronts ? 1) possible bank contagion via nervy senior creditors and depositors fearful of bail-ins at the region?s weakest institutions; 2) an unwelcome rise in the cost of borrowing for European banks who remain far more levered than US peers and are already grinding down balance sheets to the detriment of the hobbled European economy; and 3) likely heavy economic and social pressures in Cyprus going forward that, like Greece, increase euro exit risk to some degree. Add reasonable concerns about the credibility and coherence of euro policymaking during this latest episode and a side-order of German/Dutch ?orthodoxy? in sharp relief and it all looks a bit rum again.

Yet the reaction of world markets has been relatively calm so far. Wall St is still stalking record highs through it all for example as signs of the ongoing US recovery mount. So what gives? Today?s price action was interesting in that it started to show investors discriminating against European assets per se ? most visible in the inability of European stocks to follow Wall St higher and lunge lower in euro/dollar exchange rate. European bank stocks and bonds have been knocked back relatively sharply this week post-Dijsselbloem too. If this decoupling pattern were to continue, it will remain a story of the size of the economic hit and relative underperformance. But that would change if concerns morphed into euro exit and broader systemic fears and prepare for global markets at large to feel the heat again too. We?re not back there yet with the benefit of the doubt on OMTs and pressured policy reactions still largely conceded. But many of the underlying movements that might feed system-wide stresses ? what some term a ?slow panic? like deposit shifts etc ? will be impossible to monitor systematically by investors for many weeks yet and so nervy times are ahead as we enter Q2 after the Easter break.

Cyprus and European banks aside, next week will be about the US employment report and three of the Big Four central banks meeting Thurs. Will the ECB respond to the banking sector and consumer sentiment threats and ease rates or monetary conditions? It has plenty of real sector and inflation evidence already that Q1 underwhelmed in euro. The BoJ meeting will be as important with new governor Haruhiko Kuroda at the helm for the first time amid intense interest in how he will pursue the bank?s new aggressive reflation mandate.

Next week?s big events and data points:

Kenya Supreme Court rules on election outcome Sat

US/China March final manufacturing PMI Mon

Australia rate decision Tues

European March final manufacturing PMI Tues

EZ/Italy Feb jobless Tues

UK Feb mortgage and credit data Tues

German March CPI Tues

Thailand rate decision Weds

US ADP jobs/March final services PMIs Weds

European March final services PMIs Thurs

Spain/France government bond auction Thurs

ECB/BOJ/BOE decisions/pressers Thurs

EZ Feb retail sales Fri

US March employment report Fri

????

Source: http://blogs.reuters.com/globalinvesting/2013/03/28/weekly-radar-slow-panic-feared-on-cyrprus-as-central-banks-meet-and-us-reports-jobless/

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Woman returns $30,000 she found in donated clothes

Mar 26 (Reuters) - Leading money winners on the 2013 PGATour on Monday (U.S. unless stated): 1. Tiger Woods $3,787,600 2. Brandt Snedeker $2,859,920 3. Matt Kuchar $2,154,500 4. Steve Stricker $1,820,000 5. Phil Mickelson $1,650,260 6. Hunter Mahan $1,553,965 7. John Merrick $1,343,514 8. Dustin Johnson $1,330,507 9. Russell Henley $1,313,280 10. Kevin Streelman $1,310,343 11. Keegan Bradley $1,274,593 12. Charles Howell III $1,256,373 13. Michael Thompson $1,254,669 14. Brian Gay $1,171,721 15. Justin Rose $1,155,550 16. Jason Day $1,115,565 17. Chris Kirk $1,097,053 18. ...

Source: http://news.yahoo.com/blogs/sideshow/woman-returns-30-000-she-finds-donated-clothes-145000837.html

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Sofia Vergara Dyes Her Hair Blonde! See the Photo

The gorgeous Modern Family star lightens up for the spring! Check out other cute and candid moments from the stars

Source: http://www.ivillage.com/celebrity-twitter-pictures/1-b-229669?dst=iv%3AiVillage%3Acelebrity-twitter-pictures-229669

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বুধবার, ২৭ মার্চ, ২০১৩

TV comedies "Girls," "Louie" headline Peabody Awards

(Reuters) - Irreverent U.S. cable television series "Girls" and "Louie" on Wednesday headlined the winners of the annual Peabody Awards, the oldest and one of the top honors in broadcasting.

The awards recognize excellence in television and radio broadcasting, as well as by webcasters, producing organizations and individuals.

HBO's "Girls," which has earned creator and star Lena Dunham, 26, two Golden Globe awards and a slew of Emmy nominations, was lauded by the Peabody panel for its "singular, decidedly unglamorous take on sex and the single girl."

Comedian Louis C.K.'s "Louie," a cult hit on FX of unconnected story lines and vignettes about a single father in the entertainment business, was praised as a "milestone of comedic reach and candor."

The Peabody panel, which also honors international and local programs, awarded a prize to WVIT-TV, an NBC affiliate in West Hartford, Connecticut, for its coverage of the elementary school mass shootings in December in nearby Newtown.

Other notable winners include British broadcaster ITV's documentary on the late BBC presenter Jimmy Savile that explored allegations of decades-long sexual abuse by the once beloved star.

The BBC science-fiction drama "Doctor Who" won an Institutional Peabody Award for its ability to evolve with the times over its some 50 years in production.

Producer Lorne Michaels, the driving force behind NBC sketch comedy series "Saturday Night Live," won an individual Peabody Award for career achievement.

The website SCOTUSblog.com, which provides analysis and archival material on the U.S. Supreme Court, also won an award and was praised as a one-stop shop for information on the court.

A 16-member board of critics, experts, and news and entertainment industry insiders select the winners of the annual awards handed out by the University of Georgia's Grady College of Journalism and Mass Communication.

The winners will be honored at a ceremony in New York on May 20.

(Reporting by Eric Kelsey; Editing by Jill Serjeant and Vicki Allen)

Source: http://news.yahoo.com/tv-comedies-girls-louie-headline-peabody-awards-174737578.html

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As the Same-Sex Marriage Question Heads to the SCOTUS?

Here is a snippet of the?amicus brief of the U.S. Conference of Catholic Bishops.

California?s Proposition 8 encourages and supports the union of one man and one woman, as distinct from other interpersonal relationships, by giving it alone the name ?marriage.? This is rationally related to legitimate state interests for several reasons.

First, as a matter of simple biology, the union of one man and one woman is the only union capable of creating new life. Second, the People of California could reasonably conclude that a home with a mother and a father is the optimal environment for raising children, an ideal that Proposition 8 encourages and promotes. Given both the unique capacity for reproduction and unique value of homes with a mother and father, it is reasonable for a State to treat the union of one man and one woman as having a public value that is absent from other intimate interpersonal relationships.

While this Court has held that laws forbidding private, consensual, homosexual conduct between adults lack a rational basis, it does not follow that the government has a constitutional duty to encourage or endorse such conduct. Thus, governments may legitimately decide to further the interests of opposite-sex unions only. Similarly, minimum standards of rationality under the Constitution do not require adopting the lower court?s incoherent definition of ?marriage? as merely a ?committed lifelong relationship,? which is wildly over-inclusive, empties the term of its meaning, and leads to absurd results.

The lower court?s definition of ?marriage? also fails to reflect the deference to legislative decision-making that characterizes rational basis analysis generally. This is particularly egregious in a context where deference to States is especially warranted, both because marriage is a traditional concern of the States, and because ongoing controversies about marriage are currently working their way through reasonable democratic processes, yielding a range of results.

The combined force of these objectives argues for upholding Proposition 8, even if this Court were to apply a higher level of scrutiny. Marriage, understood as the union of one man and one woman, is not an historical relic, but a vital and foundational institution of civil society today. The government interests in continuing to encourage and support it are not merely legitimate, but compelling. No other institution joins together persons with the natural ability to have children, to assure that those children are properly cared for. No other institution ensures that children will at least have the opportunity of being raised by their mother and father together. Societal ills that flow from the dissolution of marriage and family would not be addressed?indeed, they would only be aggravated?were the government to fail to reinforce the union of one man and one woman with the unique encouragement and support it deserves.

Proposition 8 is not rendered invalid because some of its supporters were informed by religious or moral considerations. Many, if not most, of the significant social and political movements in our Nation?s history were based on precisely such considerations. Moreover, the argument to redefine marriage to include the union of persons of the same sex is similarly based on a combination of religious and moral considerations (albeit ones that are, in our view, flawed). As is well established in this Court?s precedent, the coincidence of law and morality, or law and religious teaching, does not detract from the rationality of a law.

Finally, redefining marriage?particularly as a matter of constitutional law, rather than legislative process?not only threatens principles of federalism and separation of powers, but would have a widespread adverse impact on other constitutional rights, such as the freedoms of religion, conscience, speech, and association. Affirmance of the judgment below would create an engine of conflict in this area, embroiling this Court and lower courts in a series of otherwise avoidable disputes?pitting constitutional right squarely against constitutional right?for years to come.

Read all 24 pages here.

For more background, basic analysis, and links to all the amicus briefs (either pro or con), head on over to SCOTUS Blog.

Source: http://www.patheos.com/blogs/yimcatholic/2013/03/as-the-same-sex-marriage-question-heads-to-the-scotus.html

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NYU Dentistry and Medicine are awarded a $840,864 collaborative grant by the Lustgarten Foundation

NYU Dentistry and Medicine are awarded a $840,864 collaborative grant by the Lustgarten Foundation [ Back to EurekAlert! ] Public release date: 26-Mar-2013
[ | E-mail | Share Share ]

Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University

'The Role of the Intestinal Microbiome in Promoting Pancreatic Carcinogenesis'

New York University College of Dentistry (NYUCD) and New York University School of Medicine (SOM) researchers have been awarded a four-year $840,864 collaborative grant by the Lustgarten Foundation to investigate a potential link between pancreatic cancer development and endogenous gut microbiota.

The co-investigators, Deepak Saxena, MS, PhD, Assistant Professor, Basic Science and Craniofacial Biology at NYUCD, and George Miller, MD, Assistant Professor; Departments of Surgery and Cell Biology at the SOM, seek to explore the links between the intestinal microbiome, Toll-like receptors (TLRs), and pancreatic cancer.

"Endogenous gut microbiota have recently been appreciated as important regulators of homeostasis in the healthy individual and contributors toward disease during microbiotic imbalance," said Saxena. "The microbiome is also emerging as a contributor to carcinogenesis in extra-pancreatic malignancies such as colon and liver cancer. However, there has been no direct link between pancreatic cancer development and endogenous gut microbiota," he noted.

There are tangential data, however, that support such an association. For example, the oral microbiome in patients with pancreatic cancer has been found to substantially differ from control subjects. Preliminary data suggest that the intestinal microbiome may be an important regulator of pancreatic cancer development in at-risk individuals.

The study proposes to:

  • Define the evolving intestinal microbiome in mice during pancreatic cancer development and progression as well as determine whether humans with pancreatic cancer harbor a distinct microbiome compared with age-matched control patients
  • Directly test whether endoluminal bacteria can affect pancreatic oncogenesis and determine whether selectively modulating the microbiome alters the rate of tumor progression
  • Test the hypothesis that luminal pathogens affect pancreatic tumorigenesis specifically via TLR ligation

"Our experiments will provide critical new information on the mechanism of pancreatic carcinogenesis in at-risk hosts and, as such, will provide guidance for pancreatic cancer prevention and possibly treatment of incipient disease," said Saxena.

"Based on our past research, we postulate that specific pathogenic gut bacteria drive pancreatic carcinogenesis in at-risk individuals via TLR activation," said Miller.

As a part of their grant, Drs. Saxena and Miller will be attending and presenting at the annual Lustgarten Scientific Conference to be held October 20-22, 2013, at the Banbury Center on Long Island NY.

###

About New York University College of Dentistry--New York University College of Dentistry (NYUCD) is the third oldest and the largest dental school in the US, educating more than 8 percent of all dentists. NYUCD has a significant global reach and provides a level of national and international diversity among its students that is unmatched by any other dental school.

About the NYU School of Medicine --NYU School of Medicine (SOM) is one of the nation's preeminent academic institutions dedicated to achieving world class medical educational excellence. For 171 years, NYU School of Medicine has trained thousands of physicians and scientists who have helped to shape the course of medical history and enrich the lives of countless people. An integral part of NYU Langone Medical Center, the School of Medicine at its core is committed to improving the human condition through medical education, scientific research and direct patient care. The School also maintains academic affiliations with area hospitals, including Bellevue Hospital Center, one of the nation's finest municipal hospitals where its students, residents and faculty provide the clinical and emergency care to New York City's diverse population, which enhances the scope and quality of their medical education and training. Additional information about the NYU School of Medicine is available at http://school.med.nyu.edu/.

About the Lustgarten Foundation: To advance the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer by: Increasing funding and support of research into the biological mechanisms and clinical strategies related to the prevention, diagnosis, and treatment of pancreatic cancer; Facilitating and enhancing the dialogue among members of the medical and scientific communities about basic and clinical research efforts that relate to pancreatic cancer; Heightening public awareness of pancreatic cancer diagnosis, treatment, and prevention and providing informational support for pancreatic cancer patients, their families, and friends.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


NYU Dentistry and Medicine are awarded a $840,864 collaborative grant by the Lustgarten Foundation [ Back to EurekAlert! ] Public release date: 26-Mar-2013
[ | E-mail | Share Share ]

Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University

'The Role of the Intestinal Microbiome in Promoting Pancreatic Carcinogenesis'

New York University College of Dentistry (NYUCD) and New York University School of Medicine (SOM) researchers have been awarded a four-year $840,864 collaborative grant by the Lustgarten Foundation to investigate a potential link between pancreatic cancer development and endogenous gut microbiota.

The co-investigators, Deepak Saxena, MS, PhD, Assistant Professor, Basic Science and Craniofacial Biology at NYUCD, and George Miller, MD, Assistant Professor; Departments of Surgery and Cell Biology at the SOM, seek to explore the links between the intestinal microbiome, Toll-like receptors (TLRs), and pancreatic cancer.

"Endogenous gut microbiota have recently been appreciated as important regulators of homeostasis in the healthy individual and contributors toward disease during microbiotic imbalance," said Saxena. "The microbiome is also emerging as a contributor to carcinogenesis in extra-pancreatic malignancies such as colon and liver cancer. However, there has been no direct link between pancreatic cancer development and endogenous gut microbiota," he noted.

There are tangential data, however, that support such an association. For example, the oral microbiome in patients with pancreatic cancer has been found to substantially differ from control subjects. Preliminary data suggest that the intestinal microbiome may be an important regulator of pancreatic cancer development in at-risk individuals.

The study proposes to:

  • Define the evolving intestinal microbiome in mice during pancreatic cancer development and progression as well as determine whether humans with pancreatic cancer harbor a distinct microbiome compared with age-matched control patients
  • Directly test whether endoluminal bacteria can affect pancreatic oncogenesis and determine whether selectively modulating the microbiome alters the rate of tumor progression
  • Test the hypothesis that luminal pathogens affect pancreatic tumorigenesis specifically via TLR ligation

"Our experiments will provide critical new information on the mechanism of pancreatic carcinogenesis in at-risk hosts and, as such, will provide guidance for pancreatic cancer prevention and possibly treatment of incipient disease," said Saxena.

"Based on our past research, we postulate that specific pathogenic gut bacteria drive pancreatic carcinogenesis in at-risk individuals via TLR activation," said Miller.

As a part of their grant, Drs. Saxena and Miller will be attending and presenting at the annual Lustgarten Scientific Conference to be held October 20-22, 2013, at the Banbury Center on Long Island NY.

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About New York University College of Dentistry--New York University College of Dentistry (NYUCD) is the third oldest and the largest dental school in the US, educating more than 8 percent of all dentists. NYUCD has a significant global reach and provides a level of national and international diversity among its students that is unmatched by any other dental school.

About the NYU School of Medicine --NYU School of Medicine (SOM) is one of the nation's preeminent academic institutions dedicated to achieving world class medical educational excellence. For 171 years, NYU School of Medicine has trained thousands of physicians and scientists who have helped to shape the course of medical history and enrich the lives of countless people. An integral part of NYU Langone Medical Center, the School of Medicine at its core is committed to improving the human condition through medical education, scientific research and direct patient care. The School also maintains academic affiliations with area hospitals, including Bellevue Hospital Center, one of the nation's finest municipal hospitals where its students, residents and faculty provide the clinical and emergency care to New York City's diverse population, which enhances the scope and quality of their medical education and training. Additional information about the NYU School of Medicine is available at http://school.med.nyu.edu/.

About the Lustgarten Foundation: To advance the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer by: Increasing funding and support of research into the biological mechanisms and clinical strategies related to the prevention, diagnosis, and treatment of pancreatic cancer; Facilitating and enhancing the dialogue among members of the medical and scientific communities about basic and clinical research efforts that relate to pancreatic cancer; Heightening public awareness of pancreatic cancer diagnosis, treatment, and prevention and providing informational support for pancreatic cancer patients, their families, and friends.


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Source: http://www.eurekalert.org/pub_releases/2013-03/nyu-nda032613.php

Jesuits percy harvin percy harvin mike wallace mike wallace Paul Bearer Cnn.com